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TORC1 Monoclonal Antibody, 100ul[BT-MCA1214] Micro Centrifuge Tubes where it is involved in

SKU: 78602044243

4.3
PLN153.50 PLN199.50

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TORC1 Monoclonal Antibody, 100ul[BT-MCA1214] Micro Centrifuge Tubes where it is involved inA chromosomal aberration involving CRTC1 is found in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. Translocation t(11 19)(q21 p13) with MAML2. The fusion protein consists of the N terminus of CRTC1 joined to the C terminus of MAML2. The reciprocal fusion protein consisting of the N terminus of MAML2 joined to the C terminus of CRTC1 has been detected in a small number of mucoepidermoid carcinomas.,function:

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Description

where it is involved in the conversion of NFkappa B p50-p65 heterodimers to p50-p50 and p65-p65 homodimers

The loss of this protein correlates with uncontrolled cell growth and tumor formation

with more than one phenotype being observed in cases falling into particular complementation groups

Thymine-DNA glycosylase (TDG) removes thymine moieties from G/T mismatches by hydrolyzing the carbon-nitrogen bond between the sugar-phosphate backbone of DNA and the mispaired thymine

Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene

TORC1 Monoclonal Antibody, 100ul[BT-MCA1214] Micro Centrifuge Tubes where it is involved inA chromosomal aberration involving CRTC1 is found in mucoepidermoid carcinomas, benign Warthin tumors and clear cell hidradenomas. Translocation t(11 19)(q21 p13) with MAML2. The fusion protein consists of the N terminus of CRTC1 joined to the C terminus of MAML2. The reciprocal fusion protein consisting of the N terminus of MAML2 joined to the C terminus of CRTC1 has been detected in a small number of mucoepidermoid carcinomas.,function:

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