MSK1(Phospho Ser212) Polyclonal Antibody, 20ul Deep Well Plates Mutations in this gene cause

Mutations in this gene cause cerebellar ataxia in humans

The enzyme is composed of a heavy chain and a light chain

and is caused by mutations in the WAS gene

PAK proteins are critical effectors that link Rho GTPases to cytoskeleton reorganization and nuclear signaling

Among its related pathways are Vesicle-mediated transport and Translocation of GLUT4 to the plasma membrane

MSK1(Phospho Ser212) Polyclonal Antibody, 20ul Deep Well Plates Mutations in this gene causeCatalytic activity: ATP + a protein = ADP + a phosphoprotein.,cofactor: Magnesium.,enzyme regulation: Appears to be activated by multiple phosphorylations on threonine and serine residues. ERK1 2 and MAPK14 p38 alpha may play a role in this process.,Serine threonine kinase required for the mitogen or stress induced phosphorylation of the transcription factors CREB (cAMP response element binding protein) and ATF1 (activating transcription factor 1).