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CA VIII Polyclonal Antibody, 20ul Enzyme Activity Assays Elevate your lab work withThe protein encoded by CA8 (carbonic anhydrase 8) was initially named CA related protein because of sequence similarity to other known carbonic anhydrase genes. However, the gene product lacks carbonic anhydrase activity (i. e. The reversible hydration of carbon dioxide). The gene product continues to carry a carbonic anhydrase designation based on clear sequence identity to other members of the carbonic anhydrase gene family. The absence of CA8 gene