Frizzled-4 Polyclonal Antibody, 50ul[BT-AP03361] Immunology TBC1D1 is the founding member

TBC1D1 is the founding member of a family of proteins sharing a 180- to 200-amino acid TBC domain presumed to have a role in regulating cell growth and differentiation

subcellular location:Associated with nucleus as well as plasma membrane

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which is critical for proper mineralization of bone and dentin

Frizzled-4 Polyclonal Antibody, 50ul[BT-AP03361] Immunology TBC1D1 is the founding memberFZD4 (frizzled class receptor 4) is a member of the frizzled gene family. Members of this family encode seven transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant