FoxA2 Monoclonal Antibody, 100ul Glassware Several alternatively spliced transcript variants

Several alternatively spliced transcript variants encoding different membrane-bound and soluble isoforms have been described for this gene

ALK/NPM1 (chromosome 5)

and seven LRRs (aa 739-988)

which is a nuclear ribonucleoprotein complex that functions in pre-mRNA splicing

which is involved in the cyclic AMP pathway

FoxA2 Monoclonal Antibody, 100ul Glassware Several alternatively spliced transcript variantsThis gene encodes a member of the forkhead class of DNA binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity onset diabetes of the young.