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AMID Polyclonal Antibody, 100ul Molecular Sciences RAN coactivation of the AR

SKU: 77826358743

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AMID Polyclonal Antibody, 100ul Molecular Sciences RAN coactivation of the ARAIFM2 encodes a flavoprotein oxidoreductase (apoptosis inducing factor, mitochondria associated 2) that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of AIFM2 is also found to be induced by tumor suppressor protein p53 in colon cancer cells.

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Description

RAN coactivation of the AR diminishes with polyglutamine expansion within the AR

Thr-718 (activation loop of the kinase domain) and Thr-860 (turn motif)

It is found to induce the expression of BCL2L1/BCL-X (L)

This syndrome is characterized by a profuse sweating after exposure to cold as well as congenital physical abnormalities of the head and spine

The protein localizes to the nucleus

AMID Polyclonal Antibody, 100ul Molecular Sciences RAN coactivation of the ARAIFM2 encodes a flavoprotein oxidoreductase (apoptosis inducing factor, mitochondria associated 2) that binds single stranded DNA and is thought to contribute to apoptosis in the presence of bacterial and viral DNA. The expression of AIFM2 is also found to be induced by tumor suppressor protein p53 in colon cancer cells.

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