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p53 Polyclonal Antibody, 20ul[BT-AP06810] Hepatocytes and six HCF repeats

SKU: 77813058439

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USD111.00 USD149.00

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p53 Polyclonal Antibody, 20ul[BT-AP06810] Hepatocytes and six HCF repeatsTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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Description

and six HCF repeats

The nuclear-encoded DNA pol γ is the only DNA polymerase required for the replication of the mitochondrial DNA

It is an integral membrane protein functioning as a receptor

ccessory component of a P4-ATPase flippase complex which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids

Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency

p53 Polyclonal Antibody, 20ul[BT-AP06810] Hepatocytes and six HCF repeatsTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni

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