PO2F3 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance SCF(FBXO33) directs ubiquitination of YBX1

SCF(FBXO33) directs ubiquitination of YBX1 (By similarity)

The encoded protein responds little or not at all to dopamine

and has been shown to form dimers/oligomers through its leucine-zipper motif

The encoded protein is important in hematopoiesis

The protein has substantial GAP activity towards several Rho-family GTPases in vitro

PO2F3 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance SCF(FBXO33) directs ubiquitination of YBX1This gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type specific differentiation pathways. The encoded protein is primarily expressed in the epidermis and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein and aberrant promoter methylation of this gene