JAK2 Monoclonal Antibody, 100ul Mechanical Pipette Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants have been identified in this gene

and presentation of the CGRP receptor to the cell surface

The protein encoded by this gene belongs to the SECY/SEC61- alpha family

Mutations in this gene have been associated with medulloblastomas

activate mitogen-activated protein kinase (MAPK)

JAK2 Monoclonal Antibody, 100ul Mechanical Pipette Multiple alternatively spliced transcript variantsThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.