PIG-Y Polyclonal Antibody, 100ul Bio-Reaction Tube The encoded protein plays a

The encoded protein plays a role in the oxidative stress response as a regulator of the transcription factor Nrf2| and expression of this gene may play a role in malignant transformation

contains a mixture of immunoglobulin and fibronectin repeats

Mutations in this gene have been associated with Parkinson disease-8

It also interacts with multiple proteins including calmodulin| CABP1| enkurin| Na(+)-H+ exchange regulatory factor (NHERF )| interferon-induced GTP-binding protein (MX1)| ring finger protein 24 (RNF24)| and SEC14 domain and spectrin repeat-containing protein 1 (SESTD1)

These enzymes also act as RNA chaperones| facilitating the correct folding and assembly of tRNAs (McCleverty et al

PIG-Y Polyclonal Antibody, 100ul Bio-Reaction Tube The encoded protein plays aThe protein encoded by PIGY (phosphatidylinositol glycan anchor biosynthesis class Y)is part of the GPI N acetylglucosaminyltransferase (GIP GnT) complex which initiates the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is synthesized in the endoplasmic reticulum and serves as an anchor for many surface proteins. Proteins containing GPI anchors can have an important role in cell cell interactions. The transcript for PIGY is bicistronic. The