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EHMT2 Polyclonal Antibody, 50ul Cellular Function Assays Several transcript variants are resulted

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EHMT2 Polyclonal Antibody, 50ul Cellular Function Assays Several transcript variants are resultedThis gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants.

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Description

Several transcript variants are resulted from alternative splicing of SIRT2

GAS8 includes 11 exons spanning 25 kb and maps to a region of chromosome 16 that is sometimes deleted in breast and prostrate cancer

Mutations in ATP7A are associated with Menkes disease

which plays an important role in maintenance of muscle structure and function

|PTM:The N-terminal processed form GRO-beta(5-73) is produced by proteolytic cleavage after secretion from bone marrow stromal cells

EHMT2 Polyclonal Antibody, 50ul Cellular Function Assays Several transcript variants are resultedThis gene encodes a methyltransferase that methylates lysine residues of histone H3. Methylation of H3 at lysine 9 by this protein results in recruitment of additional epigenetic regulators and repression of transcription. This gene was initially thought to be two different genes, NG36 and G9a, adjacent to each other in the HLA locus. Alternative splicing results in multiple transcript variants.

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