Lamin B1 Polyclonal Antibody, 100ul[BT-AP04936] Antibodies Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene

Binding of the encoded protein by filamin A targets it to sites of membrane protrusion

Alternatively spliced transcript variants encoding different isoforms have been found for SERPINE1

This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues

Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance

Lamin B1 Polyclonal Antibody, 100ul[BT-AP04936] Antibodies Alternatively spliced transcript variants encodingLMNB1 encodes one of the two B type lamin proteins and is a component of the nuclear lamina. A duplication of LMNB1 is associated with autosomal dominant adult onset leukodystrophy (ADLD). Alternative splicing results in multiple transcript variants.