Nibrin(Phospho Ser278) Polyclonal Antibody, 50ul Human Genome Knockout Libraries two TUDOR domains

two TUDOR domains

Members of this family of proteins are associated with complex assembly| protein folding| and export

In the elongating spermatid it is associated with the manchette

The encoded protein may also have a role in promoting cell growth under certain conditions and may be an important target for the RAS signaling pathways

and COA to ensure the highest quality

Nibrin(Phospho Ser278) Polyclonal Antibody, 50ul Human Genome Knockout Libraries two TUDOR domainsMutations in this gene are associated with Nijmegen breakage syndrome an autosomal recessive chromosomal instability syndrome characterized by microcephaly growth retardation immunodeficiency and cancer predisposition. The encoded protein is a member of the MRE11 RAD50 double strand break repair complex which consists of 5 proteins. This gene product is thought to be involved in DNA double strand break repair and DNA damage induced checkpoint