LATS1(Phospho-Thr1079) Rabbit Polyclonal Antibody, 50ul Pasteur Pipets Levels of the encoded protein

Levels of the encoded protein have been found to be lower in cancerous tissue and associated with metastasis suggesting a tumor suppressor function (PMID: 19956863

this protein is predominantly expressed in the sebaceous gland of the skin

The encoded protein is involved in platelet activation and controls the expression of interleukin-2

SLC25A11 contains 3 solcar repeats

Knockout studies in mice suggested that this protein inhibits embryonic oligodendrocyte precursor migration in developing spinal cord

LATS1(Phospho-Thr1079) Rabbit Polyclonal Antibody, 50ul Pasteur Pipets Levels of the encoded proteinThe protein encoded by this gene is a putative serine threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell cycle dependent manner with late prophase phosphorylation remaining through metaphase. The N terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity indicating a role as a negative