BACE(Phospho Ser498) Rabbit Polyclonal Antibody, 50ul Antibody Humanization Binds both pre-mRNA and spliced

Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions

PGC (progastricsin) encodes an aspartic proteinase that belongs to the peptidase family A1

The catalytic activity of this protein is diminished by DNA damage and by blockage of DNA replication

It has structural similarity to the membrane-associated guanylate kinase homologue (MAGUK) family

Can also act on the LYN and FYN kinases

BACE(Phospho Ser498) Rabbit Polyclonal Antibody, 50ul Antibody Humanization Binds both pre-mRNA and splicedThis gene encodes a member of the peptidase A1 family of aspartic proteases. Alternative splicing results in multiple transcript variants at least one of which encodes a preproprotein that is proteolytically processed to generate the mature protease. This transmembrane protease catalyzes the first step in the formation of amyloid beta peptide from amyloid precursor protein. Amyloid beta peptides are the main constituent of amyloid beta plaques which