PXR Polyclonal Antibody, 100ul General Lab Use SAPS1 and SAPS3

SAPS1 and SAPS3

and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins

|PTM:Phosphorylation has no effect on Catalytic activity

the protein associates with spindle microtubules near the centrosomes

Alternatively-spliced transcript variants have been observed

PXR Polyclonal Antibody, 100ul General Lab Use SAPS1 and SAPS3This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand binding domain and a DNA binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9 cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including