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MARCH2 Polyclonal Antibody, 50ul Glassware This gene is expressed in

SKU: 75996723123

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MARCH2 Polyclonal Antibody, 50ul Glassware This gene is expressed inMARCH2 (membrane associated ring CH type finger 2) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome to trans Golgi network (TGN) trafficking.

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Description

This gene is expressed in kidney and brain

CEP57 (centrosomal protein 57) encodes a cytoplasmic protein called Translokin

suggesting diverse functions in signal transduction

NPHP4 encodes a protein involved in renal tubular development and function

lacking the N-terminal hydrophobic region but retaining the same activity

MARCH2 Polyclonal Antibody, 50ul Glassware This gene is expressed inMARCH2 (membrane associated ring CH type finger 2) is a member of the MARCH family of membrane bound E3 ubiquitin ligases. MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH2 reduces surface accumulation of several glycoproteins and appears to regulate early endosome to trans Golgi network (TGN) trafficking.

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