HSC70 Monoclonal Antibody(8G7), 50ul Vessels CBP and p300 are large

CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation

Known functions for this protein include a role in aggregate formation of expanded polyglutamine proteins and the suppression of apoptosis in polyglutamine diseases

Abnormalities in RNA editing of this gene have been detected in victims of suicide that suffer from depression

muscleprovided by is a pyruvate kinase that catalyzes the transfer of a phosphoryl group from phosphoenolpyruvate to ADP

Mutations in the gene encoding ataxin 3 are associated with Machado-Joseph disease

HSC70 Monoclonal Antibody(8G7), 50ul Vessels CBP and p300 are largeThis gene encodes a member of the heat shock protein 70 family, which contains both heat inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin coated vesicles during transport of membrane components