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PGE synthase Polyclonal Antibody, 50ul Human Genome Knockout Libraries Ankyrin repeat and protein kinase

SKU: 7543537049

4.0
EUR185.00 EUR212.00

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PGE synthase Polyclonal Antibody, 50ul Human Genome Knockout Libraries Ankyrin repeat and protein kinaseProstaglandin E synthase encoded by PTGES is a glutathione dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain

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Description

Ankyrin repeat and protein kinase domain-containing protein 1 encoded by ANKK1 belongs to the Ser/Thr protein kinase family

This enzyme is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense

The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide

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The protein is essential for most innate immune responses

PGE synthase Polyclonal Antibody, 50ul Human Genome Knockout Libraries Ankyrin repeat and protein kinaseProstaglandin E synthase encoded by PTGES is a glutathione dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain

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