RIPK3 Polyclonal Antibody, 20ul Variant Libraries The protein encoded by CTSL

The protein encoded by CTSL is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism

DGK-epsilon is expressed predominantly in testis

The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain

The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1)

This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family

RIPK3 Polyclonal Antibody, 20ul Variant Libraries The protein encoded by CTSLThe product of this gene is a member of the receptor interacting protein (RIP) family of serine threonine protein kinases, and contains a C terminal domain unique from other RIP family members. The encoded protein is predominantly localized to the cytoplasm, and can undergo nucleocytoplasmic shuttling dependent on novel nuclear localization and export signals. It is a component of the tumor necrosis factor (TNF) receptor I signaling complex, and can