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p53(Phospho Ser9) Polyclonal Antibody, 50ul Organelle Studies In vertebrates| sister chromatid cohesion

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p53(Phospho Ser9) Polyclonal Antibody, 50ul Organelle Studies In vertebrates| sister chromatid cohesionThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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Description

In vertebrates| sister chromatid cohesion is released in 2 steps via distinct mechanisms

FDCSP encodes a small secreted protein that is expressed in follicular dendritic cells

including type II diabetes

it lacks the conserved His residue which is normally found 9 residues before the catalytic His

Unessential component of the TORC1 complex and essential component of the TORC2 complex

p53(Phospho Ser9) Polyclonal Antibody, 50ul Organelle Studies In vertebrates| sister chromatid cohesionThis gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni syndrome.

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