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Rb(Phospho Thr826) Polyclonal Antibody, 50ul Pipette Controller Germline mutations in this gene

SKU: 75029944728

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USD162.00 USD182.00

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Rb(Phospho Thr826) Polyclonal Antibody, 50ul Pipette Controller Germline mutations in this geneThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

Germline mutations in this gene may be associated with tumor predisposition syndrome (TPDS)| which involves increased risk of cancers including malignant mesothelioma| uveal melanoma and cutaneous melanoma

This powerful kit enables you to accurately measure human IL-1β levels and maximize stability with proper storage at 2-8℃

PTM:Proteolytically cleaved by caspase-8 during TNF-induced apoptosis

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Adjustable vacuum level with indicator light is designed for various applications

Rb(Phospho Thr826) Polyclonal Antibody, 50ul Pipette Controller Germline mutations in this geneThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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