MSH2 Monoclonal Antibody, 100ul Sampling Tubes The human pregnancy-specific glycoproteins (PSGs)

The human pregnancy-specific glycoproteins (PSGs) are a group of molecules that are mainly produced by the placental syncytiotrophoblasts during pregnancy

DFF becomes activated when DFFA is cleaved by caspase-3

In response to DNA damage and replication blocks| cell cycle progression is halted through the control of critical cell cycle regulators

Also acts as a regulator of cell polarity

consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III)

MSH2 Monoclonal Antibody, 100ul Sampling Tubes The human pregnancy-specific glycoproteins (PSGs)This locus is frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). When cloned, it was discovered to be a human homolog of the E. coli mismatch repair gene mutS, consistent with the characteristic alterations in microsatellite sequences (RER+ phenotype) found in HNPCC. Two transcript variants encoding different isoforms have been found for this gene.