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3BP2 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This KRT6 gene in particular

SKU: 7477609026

4.2
PLN185.00 PLN212.00

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3BP2 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This KRT6 gene in particularThe protein encoded by this gene has an N terminal pleckstrin homology (PH) domain an SH3 binding proline rich region and a C terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T natural killer (NK) and basophilic cells. Mutations in this gene result in cherubism. Multiple

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Description

This KRT6 gene in particular encodes the most abundant isoform

can act both as an aminopeptidase and as an endopeptidase

and act as BMP (bone morphogenetic protein) antagonists by binding to BMPs and preventing them from interacting with their receptors

While it may be a target for immunotherapy| the function of this gene is unknown

These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood

3BP2 Polyclonal Antibody, 50ul Polyclonal Antibody Preparation This KRT6 gene in particularThe protein encoded by this gene has an N terminal pleckstrin homology (PH) domain an SH3 binding proline rich region and a C terminal SH2 domain. The protein binds to the SH3 domains of several proteins including the ABL1 and SYK protein tyrosine kinases and functions as a cytoplasmic adaptor protein to positively regulate transcriptional activity in T natural killer (NK) and basophilic cells. Mutations in this gene result in cherubism. Multiple

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