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JIP-3 Polyclonal Antibody, 100ul Enzymes This gene encodes a cytoskeletal

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JIP-3 Polyclonal Antibody, 100ul Enzymes This gene encodes a cytoskeletalC Jun amino terminal kinase interacting protein 3 encoded by MAPK8IP3 shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart

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Description

This gene encodes a cytoskeletal protein that is concentrated in areas of cell-substratum and cell-cell contacts

The expression of this gene appears to be restricted to spermatocytes

Two different clinical disorders have been attributed to a defect of branched-chain amino acid transamination: hypervalinemia and hyperleucine-isoleucinemia

Several transcript variants encoding different isoforms have been found for SHC1

This protein therefore plays a role in the rapid nongenomic signaling events widely observed following stimulation of cells and tissues with estrogen

JIP-3 Polyclonal Antibody, 100ul Enzymes This gene encodes a cytoskeletalC Jun amino terminal kinase interacting protein 3 encoded by MAPK8IP3 shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart

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