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Clock Monoclonal Antibody, 100ul Vortex Mixer The encoded protein is part

SKU: 74538499539

4.3
SEK118.00 SEK158.00

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Clock Monoclonal Antibody, 100ul Vortex Mixer The encoded protein is partThe protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix loop helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes.

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Description

The encoded protein is part of the large ATP-dependent chromatin remodeling complex SNF/SWI and has sequence similarity to the yeast Swp73 protein

Mutation or amplification of REL is associated with B-cell lymphomas

The Mediator complex interacts with DNA-binding gene-specific transcription factors to modulate transcription by RNA polymerase II

Mutations in COL3A1 are associated with Ehlers-Danlos syndrome types IV

The encoded protease may play a role in the proteolytic processing of pulmonary surfactant protein B in the lung and may function in protein catabolism in the renal proximal tubules

Clock Monoclonal Antibody, 100ul Vortex Mixer The encoded protein is partThe protein encoded by this gene plays a central role in the regulation of circadian rhythms. The protein encodes a transcription factor of the basic helix loop helix (bHLH) family and contains DNA binding histone acetyltransferase activity. The encoded protein forms a heterodimer with ARNTL (BMAL1) that binds E box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes.

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