Arylsulfatase A Polyclonal Antibody, 100ul Immune Cell Analysis SIN3B (SIN3 Transcription Regulator Family

SIN3B (SIN3 Transcription Regulator Family Member B) is a Protein Coding gene

An important paralog of this gene is ZNF169

Members of this protein family are known to be involved in various kinds of spindle dynamics

Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene

This gene encodes a member of the membrane-bound O-acyltransferases family of integral membrane proteins that have acyltransferase activity

Arylsulfatase A Polyclonal Antibody, 100ul Immune Cell Analysis SIN3B (SIN3 Transcription Regulator FamilyThe protein encoded by ARSA hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene.