IRE1 Alpha Monoclonal Antibody, 50ul Sealing Film Multiple transcript variants due to

Multiple transcript variants due to alternative promoters and alternative splicing have been found for this gene

Exhibits low fidelity and efficiency opposite a thymidine template

The ubiquitination factor E4A is involved in multiubiquitin chain assembly and plays a critical role in chromosome condensation and separation through the polyubiquitination of securin

This protein is specifically expressed in platelets and megakaryocytes and may be involved in proplatelet production and platelet release

This gene encodes an alpha 1 subunit

IRE1 Alpha Monoclonal Antibody, 50ul Sealing Film Multiple transcript variants due toThe protein encoded by this gene is the ER to nucleus signalling 1 protein, a human homologue of the yeast Ire1 gene product. This protein possesses intrinsic kinase activity and an endoribonuclease activity and it is important in altering gene expression as a response to endoplasmic reticulum based stress signals.