CPI-17(Phospho Thr38) Polyclonal Antibody, 100ul Peptide Synthesis PTK2B encodes a cytoplasmic protein

PTK2B encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway

Methylation of the CpG island leads to transcriptional silencing of this gene

The encoded protein (cadherin 19) is a calcium dependent cell-cell adhesion glycoprotein containing five extracellular cadherin repeats

Studies in rat indicate that translation of this mRNA initiates at a non-AUG (CUG) codon

Made from GPPS material

CPI-17(Phospho Thr38) Polyclonal Antibody, 100ul Peptide Synthesis PTK2B encodes a cytoplasmic proteinThe protein encoded by this gene belongs to the protein phosphatase 1 (PP1) inhibitor family. This protein is an inhibitor of smooth muscle myosin phosphatase, and has higher inhibitory activity when phosphorylated. Inhibition of myosin phosphatase leads to increased myosin phosphorylation and enhanced smooth muscle contraction. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.