CaV alpha2delta2 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) BCL-2 family members are known

BCL-2 family members are known to be regulators of programmed cell death

Three alternatively spliced transcript variants encoding different isoforms have been found for this gene

Expansion of a 20 amino acid polyalanine tract in this protein by 5-13 aa has been associated with congenital central hypoventilation syndrome

This protein mediates the signal of the transforming growth factor (TGF)-beta| and thus regulates multiple cellular processes| such as cell proliferation| apoptosis| and differentiation

The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system

CaV alpha2delta2 Polyclonal Antibody, 50ul Centrifuge Tube (Bottle) BCL-2 family members are knownCalcium channels mediate the entry of calcium ions into the cell upon membrane polarization. This gene encodes the alpha 2 delta subunit of the voltage dependent calcium channel complex. The complex consists of the main channel forming subunit alpha 1, and auxiliary subunits alpha 2 delta, beta, and gamma. The auxiliary subunits function in the assembly and membrane localization of the complex, and modulate calcium currents and channel activation