PLC gamma2(Phospho Tyr753) Polyclonal Antibody, 100ul Mammalian Expression a renal disease

a renal disease

TLEs contain several WD-repeats implicated in protein-protein interaction

members of which are small molecular weight guanosine triphosphatases (GTPases) that contain highly conserved domains involved in GTP binding and hydrolysis

This protein also suppresses tumor growth in human ovarian carcinoma

tissue specificity:Strongly expressed in heart

PLC gamma2(Phospho Tyr753) Polyclonal Antibody, 100ul Mammalian Expression a renal diseaseThe protein encoded by this gene is a transmembrane signaling enzyme that catalyzes the conversion of 1 phosphatidyl 1D myo inositol 4,5 bisphosphate to 1D myo inositol 1,4,5 trisphosphate (IP3) and diacylglycerol (DAG) using calcium as a cofactor. IP3 and DAG are second messenger molecules important for transmitting signals from growth factor receptors and immune system receptors across the cell membrane. Mutations in this gene have been found in