Pirh2 Monoclonal Antibody, 100ul Pathway and Network Analysis Potent inhibitor of E2F-mediated trans-activation|

Potent inhibitor of E2F-mediated trans-activation| associates preferentially with E2F5

but shuttles into the nucleus where it localizes to nuclear speckles

This gene encodes a cytoplasmic protein tyrosine kinase which is involved in calcium-induced regulation of ion channels and activation of the map kinase signaling pathway

This gene encodes a highly conserved| putative transmembrane protein

MMP peptide modified

Pirh2 Monoclonal Antibody, 100ul Pathway and Network Analysis Potent inhibitor of E2F-mediated trans-activation|The protein encoded by this gene has ubiquitin ligase activity. It mediates E3 dependent ubiquitination and proteasomal degradation of target proteins, including tumor protein 53, histone deacetylase 1, and cyclin dependent kinase inhibitor 1B, thus regulating their levels and cell cycle progression. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.