KLF8 Polyclonal Antibody, 100ul Deep Well Plates Among its related pathways are

Among its related pathways are Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 and Bacterial invasion of epithelial cells

and the ceramide metabolites sphingosine and sphingosine-1-phosphate (S1P) are important bioregulatory molecules

serine/threonine protein kinase family

Four alternatively spliced transcript variants of this gene encoding two distinct isoforms have been reported

|tissue specificity:Present mainly in tissues enriched in stratified squamous keratinising epithelium

KLF8 Polyclonal Antibody, 100ul Deep Well Plates Among its related pathways areKLF8 encodes Kruppel like factor 8 which is a member of the Sp KLF family of transcription factors. Members of this family contain a C terminal DNA binding domain with three Kruppel like zinc fingers. The Kruppel like factor 8 is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16.