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Oct-3/4 Polyclonal Antibody, 100ul[BT-AP06332] Capsule Filter This gene product is the

SKU: 72507314614

4.2
USD141.00 USD176.00

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Oct-3/4 Polyclonal Antibody, 100ul[BT-AP06332] Capsule Filter This gene product is thePOU5F1 (POU class 5 homeobox 1) encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG

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Description

This gene product is the human homolog of mouse Tbx2

where they participate in a wide range of physiologic responses

Variations in this gene have been linked to metabolic syndrome

and autosomal recessive acute recurrent myoglobinuria (ARARM)

which involves increased risk of cancers including malignant mesothelioma

Oct-3/4 Polyclonal Antibody, 100ul[BT-AP06332] Capsule Filter This gene product is thePOU5F1 (POU class 5 homeobox 1) encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of POU5F1 in adult tissues is associated with tumorigenesis. POU5F1 can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non AUG

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