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SFRS15 Polyclonal Antibody, 50ul Drug Development and Evaluation when thymine dimers are present

SKU: 72477094723

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SFRS15 Polyclonal Antibody, 50ul Drug Development and Evaluation when thymine dimers are presentSCAF4 (SR related CTD associated factor 4)likely encodes a member of the arginine serine rich splicing factor family. A similar protein in Rat appears to bind the large subunit of RNA polymerase II and provide a link between transcription and pre mRNA splicing. Alternatively spliced transcript variants have been described.

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Description

when thymine dimers are present

The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest| and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells

It can be used in environmental chambers and CO2 incubators

Additional splice variation has been identified but the full-length nature of these transcripts has not been determined

|tissue specificity:Expressed in the adult spleen| lymph node| prostate| ovary| small intestine| and colon| and in fetal heart| lung| liver and kidney

SFRS15 Polyclonal Antibody, 50ul Drug Development and Evaluation when thymine dimers are presentSCAF4 (SR related CTD associated factor 4)likely encodes a member of the arginine serine rich splicing factor family. A similar protein in Rat appears to bind the large subunit of RNA polymerase II and provide a link between transcription and pre mRNA splicing. Alternatively spliced transcript variants have been described.

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