IKK alpha(Phospho Thr23) Polyclonal Antibody, 50ul Nucleic Acid Amplification ARHGAP12 (Rho GTPase activating protein

ARHGAP12 (Rho GTPase activating protein 12) encodes a member of a large family of proteins that activate Rho-type guanosine triphosphate (GTP) metabolizing enzymes

Mutations in this gene are a cause of platelet-type bleeding disorder-11 (BDPLT11)

Arg-19 and Arg-25 are dimethylated

Cortistatin-14 seems to be a high potency ligand at this receptor

Neutrophil cytosolic factor 1 encoded by NCF1 is a 47 kDa cytosolic subunit of neutrophil NADPH oxidase

IKK alpha(Phospho Thr23) Polyclonal Antibody, 50ul Nucleic Acid Amplification ARHGAP12 (Rho GTPase activating proteinThis gene encodes a member of the serine threonine protein kinase family. The encoded protein a component of a cytokine activated protein complex that is an inhibitor of the essential transcription factor NF kappa B complex phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway thereby activating the transcription factor.