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ACSS1 Polyclonal Antibody, 20ul[BT-AP00203] Protein Research Take your research to theACSS1 encodes a mitochondrial acetyl CoA synthetase enzyme (acyl CoA synthetase short chain family member 1). A similar protein in mice plays an important role in the tricarboxylic acid cycle by catalyzing the conversion of acetate to acetyl CoA. Alternatively spliced transcript variants encoding multiple isoforms have been observed for ACSS1.