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PERK Polyclonal Antibody, 100ul[BT-AP07065] Antibodies In resting cells

SKU: 72145369611

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PERK Polyclonal Antibody, 100ul[BT-AP07065] Antibodies In resting cellsThe protein encoded by EIF2AK3 (eukaryotic translation initiation factor 2 alpha kinase 3) phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is

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Description

In resting cells

which may function to modulate the endocrine and autocrine effects of prolactin in normal tissue and cancer

GO annotations related to this gene include nucleic acid binding and exonuclease activity

a familial cardiac and skeletal myopathy (CSM)

which is known as a precursor of the cornified cell envelope

PERK Polyclonal Antibody, 100ul[BT-AP07065] Antibodies In resting cellsThe protein encoded by EIF2AK3 (eukaryotic translation initiation factor 2 alpha kinase 3) phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is

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