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DAPK1(Phospho-Ser308) Polyclonal Antibody, 100ul Protein Modification Type XXI collagen is localized

SKU: 72085845757

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DAPK1(Phospho-Ser308) Polyclonal Antibody, 100ul Protein Modification Type XXI collagen is localizedDeath associated protein kinase 1 is a positive mediator of gamma interferon induced programmed cell death. DAPK1 encodes a structurally unique 160 kD calmodulin dependent serine threonine kinase that carries 8 ankyrin repeats and 2 putative P loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants.

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Description

Type XXI collagen is localized to tissues containing type I collagen and maintains the integrity of the extracellular matrix

and it may play a role in membrane transport and signal transduction

Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta)

Polymorphism within this gene is associated with variable ability to metabolize mephenytoin

Two alternative transcript variants encoding different protein isoforms have been described for this gene

DAPK1(Phospho-Ser308) Polyclonal Antibody, 100ul Protein Modification Type XXI collagen is localizedDeath associated protein kinase 1 is a positive mediator of gamma interferon induced programmed cell death. DAPK1 encodes a structurally unique 160 kD calmodulin dependent serine threonine kinase that carries 8 ankyrin repeats and 2 putative P loop consensus sites. It is a tumor suppressor candidate. Alternative splicing results in multiple transcript variants.

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