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IκB-alpha Polyclonal Antibody, 50ul[BT-AP10544] Diagnostic Probes & Oligos targeting specific proteins for ubiquitin-mediated

SKU: 71590662458

4.4
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IκB-alpha Polyclonal Antibody, 50ul[BT-AP10544] Diagnostic Probes & Oligos targeting specific proteins for ubiquitin-mediatedThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

targeting specific proteins for ubiquitin-mediated proteolysis

and Psf3 (GINS3

This gene encodes a protein containing an alpha/beta hydrolase fold| which is a catalytic domain found in a very wide range of enzymes

The deduced sequence of the hypothetical protein of 132 aa does not share any similarity with that of functional CGB subunits (PMID:8954017)

tissue specificity:Ubiquitous with higher expression in testis

IκB-alpha Polyclonal Antibody, 50ul[BT-AP10544] Diagnostic Probes & Oligos targeting specific proteins for ubiquitin-mediatedThis gene encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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