Desmin Monoclonal Antibody(1B12), 50ul Antibodies resulting in the conversion of

resulting in the conversion of lysine to alpha-aminoadipic semialdehyde

The protein encoded by this gene has similarity to a mouse protein which suggests a role in the insertion of secretory and membrane polypeptides into the endoplasmic reticulum

intracellular N and C termini

the encoded protein contains 2-43 copies of kringle-type domains

This protease cleaves complement components C2 and C4 in order to generate C3 convertase in the lectin pathway of the complement system

Desmin Monoclonal Antibody(1B12), 50ul Antibodies resulting in the conversion ofThis gene encodes a muscle specific class III intermediate filament. Homopolymers of this protein form a stable intracytoplasmic filamentous network connecting myofibrils to each other and to the plasma membrane. Mutations in this gene are associated with desmin related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies.