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IGF2 Polyclonal Antibody, 20ul Mechanical Pipette Transducin is a 3-subunit guanine

SKU: 71333807167

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IGF2 Polyclonal Antibody, 20ul Mechanical Pipette Transducin is a 3-subunit guanineThis gene encodes a member of the insulin family of polypeptide growth factors which are involved in development and growth. It is an imprinted gene expressed only from the paternal allele and epigenetic changes at this locus are associated with Wilms tumour Beckwith Wiedemann syndrome rhabdomyosarcoma and Silver Russell syndrome. A read through INS IGF2 gene exists whose 5' region overlaps the INS gene and the 3' region overlaps this gene.

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Description

Transducin is a 3-subunit guanine nucleotide-binding protein (G protein) which stimulates the coupling of rhodopsin and cGMP-phoshodiesterase during visual impulses

Alternatively spliced transcript variants encoding distinct isoforms have been found

and it has been determined that the diseased allele contains 40-83 CAG repeats

The protein also has pro-apoptotic activity

also known as Rendu-Osler-Weber syndrome 2

IGF2 Polyclonal Antibody, 20ul Mechanical Pipette Transducin is a 3-subunit guanineThis gene encodes a member of the insulin family of polypeptide growth factors which are involved in development and growth. It is an imprinted gene expressed only from the paternal allele and epigenetic changes at this locus are associated with Wilms tumour Beckwith Wiedemann syndrome rhabdomyosarcoma and Silver Russell syndrome. A read through INS IGF2 gene exists whose 5' region overlaps the INS gene and the 3' region overlaps this gene.

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