Rb Polyclonal Antibody, 50ul[BT-AP07686] Vacuum Filter Minichromosome maintenance complex component 3

Minichromosome maintenance complex component 3 encoded by MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication

The protein functions in cap-independent translation of ornithine decarboxylase mRNA

and axon fasciculation

Mature human MEGF9 is 572 amino acids (aa) in length

Diseases associated with C1QTNF8 include brain cancer

Rb Polyclonal Antibody, 50ul[BT-AP07686] Vacuum Filter Minichromosome maintenance complex component 3The protein encoded by RB1 (RB transcriptional corepressor 1) is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in RB1 are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.