PNKD Polyclonal Antibody, 50ul Recombinant Protein A PRCC-TFE3 fusion protein is

A PRCC-TFE3 fusion protein is expressed in affected carcinomas and is likely associated with altered gene transactivation

also known as myosin light chain 2a (MLC2a)

Mutations in this gene have been shown to cause an X-linked dominant STAR syndrome that typically manifests syndactyly

which is located primarily in the endoplasmic reticulum and ubiquitously expressed with highest levels in brain

Because of the conservation of N protein sequence and its strong immunogenicity

PNKD Polyclonal Antibody, 50ul Recombinant Protein A PRCC-TFE3 fusion protein isThis gene is thought to play a role in the regulation of myofibrillogenesis. Mutations in this gene have been associated with the movement disorder paroxysmal non kinesigenic dyskinesia. Alternative splicing results in multiple transcript variants.