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IP3R-I(Phospho Ser1598) Polyclonal Antibody, 100ul Long RNA Synthesis This receptor is highly expressed

SKU: 70816006859

4.7
SEK123.75 SEK156.75

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IP3R-I(Phospho Ser1598) Polyclonal Antibody, 100ul Long RNA Synthesis This receptor is highly expressedThis gene encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

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Description

This receptor is highly expressed during embryonic development

This protein is a component of anaphase-promoting complex (APC)

and transfers it to substrates

Upregulation of this gene is associated with asthma and dysregulation may also be implicated in cancer

PubMed: 19131338

IP3R-I(Phospho Ser1598) Polyclonal Antibody, 100ul Long RNA Synthesis This receptor is highly expressedThis gene encodes an intracellular receptor for inositol 1,4,5 trisphosphate. Upon stimulation by inositol 1,4,5 trisphosphate, this receptor mediates calcium release from the endoplasmic reticulum. Mutations in this gene cause spinocerebellar ataxia type 15, a disease associated with an heterogeneous group of cerebellar disorders. Multiple transcript variants have been identified for this gene.

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