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ARK-1 Polyclonal Antibody, 20ul[BT-AP00611] Enzyme-Linked Immunosorbent Assay (ELISA) With 2000 U and 50

SKU: 70439345584

4.1
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ARK-1 Polyclonal Antibody, 20ul[BT-AP00611] Enzyme-Linked Immunosorbent Assay (ELISA) With 2000 U and 50The protein encoded by AURKA is a cell cycle regulated kinase that appears to be involved in microtubule formation and or stabilization at the spindle pole during chromosome segregation. The encoded protein (aurora kinase A) is found at the centrosome in interphase cells and at the spindle poles in mitosis. AURKA may play a role in tumor development and progression. A processed pseudogene of AURKA has been found on chromosome 1, and an unprocessed

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Description

With 2000 U and 50 U/μl

The protein encoded by this gene is another member of the angiopoietin family that is widely expressed in adult tissues with mRNA levels highest in highly vascularized tissues

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Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers

but it translocates to the nucleus during S phase of the cell cycle and associates with C-MYC

ARK-1 Polyclonal Antibody, 20ul[BT-AP00611] Enzyme-Linked Immunosorbent Assay (ELISA) With 2000 U and 50The protein encoded by AURKA is a cell cycle regulated kinase that appears to be involved in microtubule formation and or stabilization at the spindle pole during chromosome segregation. The encoded protein (aurora kinase A) is found at the centrosome in interphase cells and at the spindle poles in mitosis. AURKA may play a role in tumor development and progression. A processed pseudogene of AURKA has been found on chromosome 1, and an unprocessed

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