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Neu Polyclonal Antibody, 100ul[BT-AP05906] Roller Bottles This gene is a member

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Neu Polyclonal Antibody, 100ul[BT-AP05906] Roller Bottles This gene is a memberERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those

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Description

This gene is a member of the aggrecan/versican proteoglycan family

Stat5 is constitutively active in some leukemic cell types

Using fluorescence in situ hybridization the full length 90K cDNA has been localized to chromosome 17q25

Mutations in this gene have been associated with bone marrow failure syndrome 2

Elevated levels of baculoviral IAP repeat-containing protein 7 may be associated with cancer progression and play a role in chemotherapy sensitivity

Neu Polyclonal Antibody, 100ul[BT-AP05906] Roller Bottles This gene is a memberERBB2 encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. Receptor tyrosine protein kinase erbB 2 has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase mediated activation of downstream signalling pathways, such as those

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