CCBE1 Polyclonal Antibody, 50ul Biochemical Reagents Core 1 is a precursor

Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins

CDKN2A (cyclin dependent kinase inhibitor 2A) generates several transcript variants which differ in their first exons

Alternative splicing of TAF1 results in multiple transcript variants

and endocrine signaling as well as inhibiting the release of many hormones and other secretory proteins

The testicular form is expressed in embryonic tissues

CCBE1 Polyclonal Antibody, 50ul Biochemical Reagents Core 1 is a precursorThis gene is thought to function in extracellular matrix remodeling and migration. It is predominantly expressed in the ovary, but down regulated in ovarian cancer cell lines and primary carcinomas, suggesting its role as a tumour suppressor. Mutations in this gene have been associated with Hennekam lymphangiectasia lymphedema syndrome, a generalized lymphatic dysplasia in humans.