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WISP1 Polyclonal Antibody, 100ul Molecular Biologyn The encoded protein (deoxyhypusine synthase)

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WISP1 Polyclonal Antibody, 100ul Molecular Biologyn The encoded protein (deoxyhypusine synthase)This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine rich domains: insulin like growth factor binding domain, von Willebrand factor type C module,

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Description

The encoded protein (deoxyhypusine synthase) catalyzes the first step in hypusine formation by transferring the butylamine moiety of spermidine to a specific lysine residue of the eukaryotic translation initiation factor 5A precursor

The proteins encoded by these genes form disulfide bonds with cysteine residues in hair keratins| thereby contributing to the structure and stability of hair fibers

This gene product is predicted to be a single-pass type II Golgi membrane protein but it may also be secreted and proteolytically processed like the related proteins in mouse and Drosophila (PMID: 9187150)

the protein rapidly cycles between the plasma membrane and early endosomes

Among its related pathways are Platelet activation and Ras signaling pathway

WISP1 Polyclonal Antibody, 100ul Molecular Biologyn The encoded protein (deoxyhypusine synthase)This gene encodes a member of the WNT1 inducible signaling pathway (WISP) protein subfamily, which belongs to the connective tissue growth factor (CTGF) family. WNT1 is a member of a family of cysteine rich, glycosylated signaling proteins that mediate diverse developmental processes. The CTGF family members are characterized by four conserved cysteine rich domains: insulin like growth factor binding domain, von Willebrand factor type C module,

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