Cdk5 Monoclonal Antibody, 100ul[BT-MCA0332] CellSafe™ Mutations in this gene have

Mutations in this gene have been linked to cryptogenic cirrhosis

It contains an N-terminal caspase recruitment domain (CARD)| a centrally located nucleotide-binding domain (NBD)| and 10 tandem leucine-rich repeats (LRRs) in its C terminus

Before ligand binding

This protein may function in the differentiation of oligodendrocytes

Transcription of protein-coding genes can be reconstituted on naked DNA with only the general transcription factors and RNA polymerase II

Cdk5 Monoclonal Antibody, 100ul[BT-MCA0332] CellSafe™ Mutations in this gene haveThis gene encodes a proline directed serine threonine kinase that is a member of the cyclin dependent kinase family of proteins. Unlike other members of the family, the protein encoded by this gene does not directly control cell cycle regulation. Instead the protein, which is predominantly expressed at high levels in mammalian postmitotic central nervous system neurons, functions in diverse processes such as synaptic plasticity and neuronal migration